Characterization and Biological Activities of Ethanol Extract of Justicia  carnea

Beatrics Ihuoma Okocha; Kingsley John Orie

doi:10.60787/ijrti.vol2no1.53

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Published: 2025-04-01

DOI: https://doi.org/10.60787/ijrti.vol2no1.53

Keywords:

Active metabolites, antimicrobial, antioxidant, Justicia carnea

Beatrics Ihuoma Okocha

Department of Science Laboratory Technology, Faculty of Sciences, Federal Polytechnic, Ekowe, Nigeria

Kingsley John Orie

Department of Chemistry, Faculty of Natural and Applied Sciences, Ignatius Ajuru University, Port Harcourt, Nigeria

Abstract

For a long time, the blood tonic and other therapeutic qualities of the medicinal herb Justicia carnea have been utilized in Nigeria. The purpose of this research is to learn more about the biological activity and phytochemical profile of the Justicia carnea ethanol extract. The phytochemicals in Justicia carnea were identified using GC-MS and Fourier transform infrared spectroscopy. An 100% ethanol extraction was performed on the powdered sample, and the resulting extract was concentrated using a rotary evaporator. Among the many potential medical applications of the few active metabolites identified by the study are those for lowering inflammation, fighting diabetes, regulating the immune system, and even curing malaria. Extract from Justicia carnea was most effective against Salmonella typhi, an infectious disease, with a MIC of 0.001 mg/L. It is thought to have the most promising antioxidant properties at a concentration of 0.50 g/ml, inhibiting peroxide and superoxide radicals with an inhibition diameter of 70.41 and 74.57 mm, respectively. The therapeutic properties of Justicia carnea extract are being investigated by the medical community

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Vol. 2 No. 1 (2025)

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Articles

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

How to Cite

Okocha, B. I., & Orie, K. J. (2025). Characterization and Biological Activities of Ethanol Extract of Justicia carnea. International Journal Of Research And Technopreneurial Innovations, 2(1), 16-24. https://doi.org/10.60787/ijrti.vol2no1.53

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